One week into the latest Windows 10 update (version 1803 AKA the April 2018 Update) we're hearing of a significant number of bugs and issues update.
A short list includes problems loading Edge browser and Windows Defender; the right click function not working on taskbar items; problems with Fast Restart, plus Chrome browser hangs up and Cortana freezes up; the microphone isn't detected; mouse acceleration is different/weird; shutdown doesn't work properly, among others. (On the other hand, the 1803 update seemed to "cure" a spontaneous shutdown problem I had on my office computer before the update; I don't know why.)
What you can do: You might consider delaying the update a few weeks (or months) until Microsoft addresses some of these issues in subsequent tweaks/versions of the update. Or, if you had "automatic updates" enabled and you now have some of these problems with version 1803 you may be able to roll back to the previous version (1709) of Windows 10. Here's how: Go to Settings, choose Recovery and you'll have the choice to "Reset this PC" or "Go back to the previous version of Windows 10"; then click "Get started" to begin the roll back process.
This situation reminds me of why we don't generally recommend the "latest and greatest" technologies and "shiny object"s for our clients. We think it usually more sense to be be "fast followers" rather than "early adopters". (In spite of the "early adopter" risks, we install updates as soon as they're available to assist our clients with any problems they may have.)
Technology is wonderful; when it works.